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Oral Biolife Reports Major Breakthrough in Large Animal Study for Treating Periodontal Disease

by Mary

Oral Biolife (OBL), a biotechnology firm based in Bethlehem, Pennsylvania, has made significant strides in developing a dental treatment for both humans and animals. On October 8, 2024, the company announced promising results from a study involving its lead product, Ambrilux Dental Gel. This innovative gel has demonstrated the ability to regenerate bone in the teeth of Beagle dogs suffering from induced periodontal disease.

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In the study, radiographs were taken at three key intervals: at the start, 28 days after the first application, and 29 days after the second application. The results were striking; 100% of the treated dogs showed increased bone regeneration after both applications, while only one-third of the control group exhibited any detectable bone growth. This data is crucial as it suggests that Ambrilux could be effective in treating periodontal disease not just in animals but potentially in humans as well.

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Importantly, no adverse events or safety issues were reported during the study. An adverse event is defined as any unexpected and unfavorable observation occurring in dogs after using an investigational veterinary product.

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Bill Breitenbach, CEO of Oral Biolife, expressed his enthusiasm about these findings. “This proof-of-concept marks a major milestone in our journey. It reinforces our confidence that Ambrilux Dental Gel has the potential to revolutionize how dental care is provided,” he stated.

Periodontal disease is a widespread issue, affecting nearly 20% of the global population and 47% of adults in the United States. It incurs an estimated annual cost of $54 billion due to lost productivity. These statistics highlight a pressing need for effective non-invasive treatments for this condition.

Stella Vnook, President of Oral Biolife, emphasized the company’s mission to provide accessible dental care. “We are pleased with these promising results and are excited to continue our research to further establish the safety and efficacy of Ambrilux Dental Gel,” she said.

The advancements made by Oral Biolife represent a potential breakthrough in dental health research, aiming to address significant gaps in current treatment options for periodontal disease.

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